TRAF6 Plays a Proviral Role in Tick-Borne Flavivirus Infection through Interaction with the NS3 Protease

TRAF6 Plays a Proviral Role in Tick-Borne Flavivirus Infection through Interaction with the NS3 Protease

Summary: Tick-borne flaviviruses (TBFVs) can cause life-threatening encephalitis and hemorrhagic fever. To identify virus-host interactions that may be exploited as therapeutic targets, we analyzed the TBFV polyprotein in silico for antiviral protein-binding motifs. We obtained two putative tumor ne...

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Bibliographic Details
Main Authors: Brian H. Youseff, Thomas G. Brewer, Kristin L. McNally, Adaeze O. Izuogu, Kirk J. Lubick, John B. Presloid, Saad Alqahtani, Saurabh Chattopadhyay, Sonja M. Best, Xiche Hu, R. Travis Taylor
Format: Article
Language:English
Published: Elsevier 2019-05-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004219301476

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http://www.sciencedirect.com/science/article/pii/S2589004219301476

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