Puzzles in modern biology. V. Why are genomes overwired? [version 2; referees: 2 approved]
Many factors affect eukaryotic gene expression. Transcription factors, histone codes, DNA folding, and noncoding RNA modulate expression. Those factors interact in large, broadly connected regulatory control networks. An engineer following classical principles of control theory would design a simple...
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| Format: | Article |
| Language: | English |
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F1000 Research Ltd
2017-08-01
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| Series: | F1000Research |
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| Online Access: | https://f1000research.com/articles/6-924/v2 |