Epicatechin stimulates mitochondrial activity and selectively sensitizes cancer cells to radiation.

Radiotherapy is the treatment of choice for solid tumors including pancreatic cancer, but the effectiveness of treatment is limited by radiation resistance. Resistance to chemotherapy or radiotherapy is associated with reduced mitochondrial respiration and drugs that stimulate mitochondrial respirat...

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Bibliographic Details
Main Authors: Hosam A Elbaz, Icksoo Lee, Deborah A Antwih, Jenney Liu, Maik Hüttemann, Steven P Zielske
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3916420?pdf=render