Blood cell mitochondrial DNA content and premature ovarian aging.

Primary ovarian insufficiency (POI) is a critical fertility defect characterized by an anticipated and silent impairment of the follicular reserve, but its pathogenesis is largely unexplained. The frequent maternal inheritance of POI together with a remarkable dependence of ovarian folliculogenesis...

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Bibliographic Details
Main Authors: Marco Bonomi, Edgardo Somigliana, Chiara Cacciatore, Marta Busnelli, Raffaella Rossetti, Silvia Bonetti, Alessio Paffoni, Daniela Mari, Guido Ragni, Luca Persani, Italian Network for the study of Ovarian Dysfunctions
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3411770?pdf=render