Interaction between oxytocin receptor DNA methylation and genotype is associated with risk of postpartum depression in women without depression in pregnancy

Interaction between oxytocin receptor DNA methylation and genotype is associated with risk of postpartum depression in women without depression in pregnancy

Postpartum depression (PPD) affects up to 19% of women, negatively impacting maternal and infant health. Reductions in plasma oxytocin levels have been associated with PPD and heritability studies have established a genetic contribution. Epigenetic regulation of the oxytocin receptor gene (OXTR) has...

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Bibliographic Details
Main Authors: Aleeca F. Bell, C. Sue Carter, Colin D. Steer, Jean eGolding, John M Davis, Alana D. Steffen, Leah H. Rubin, Travis S. Lillard, Steven P. Gregory, James C. Harris, Jessica J. Connelly
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-07-01
Series:Frontiers in Genetics
Subjects:
DNA Methylation
Oxytocin
epigenetics
postpartum depression
OXTR
oxytocin receptor
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00243/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00243/full

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