A single residue substitution in the receptor-binding domain of H5N1 hemagglutinin is critical for packaging into pseudotyped lentiviral particles.

A single residue substitution in the receptor-binding domain of H5N1 hemagglutinin is critical for packaging into pseudotyped lentiviral particles.

BACKGROUND: Serological studies for influenza infection and vaccine response often involve microneutralization and hemagglutination inhibition assays to evaluate neutralizing antibodies against human and avian influenza viruses, including H5N1. We have previously characterized lentiviral particles p...

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Bibliographic Details
Main Authors: Dong-Jiang Tang, Yuen-Man Lam, Yu-Lam Siu, Chi-Hong Lam, Shui-Ling Chu, J S Malik Peiris, Philippe Buchy, Béatrice Nal, Roberto Bruzzone
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3487904?pdf=render

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http://europepmc.org/articles/PMC3487904?pdf=render

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