Platelet-to-Lymphocyte Ratio Is Associated With Favorable Response to Neoadjuvant Chemotherapy in Triple Negative Breast Cancer: A Study on 120 Patients

Platelet-to-Lymphocyte Ratio Is Associated With Favorable Response to Neoadjuvant Chemotherapy in Triple Negative Breast Cancer: A Study on 120 Patients

IntroductionTriple negative breast cancer (TNBC) is highly heterogeneous, but still most of the patients are treated by the anthracycline/taxane-based neoadjuvant therapy (NACT). Tumor-infiltrating lymphocytes (TILs) are a strong predictive and prognostic biomarker in TNBC, however are not always av...

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Bibliographic Details
Main Authors: Sejdi Lusho, Xavier Durando, Marie-Ange Mouret-Reynier, Myriam Kossai, Nathalie Lacrampe, Ioana Molnar, Frederique Penault-Llorca, Nina Radosevic-Robin, Catherine Abrial
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Oncology
Subjects:
neoadjuvant chemotherapy
pathologic complete response (pCR)
peripheral blood counts
platelet-to-lymphocyte ratio (PLR)
triple negative breast cancer (TNBC)
tumor-infiltrating lymphocytes (TILs)
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.678315/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.678315/full

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