Alpha‐Klotho, a critical protein for lung health, is not expressed in normal lung

Abstract Alpha‐Klotho (αKlotho), produced by the kidney and selected organs, is essential for tissue maintenance and protection. Homozygous αKlotho‐deficiency leads to premature multi‐organ degeneration and death; heterozygous insufficiency leads to apoptosis, oxidative stress, and increased injury...

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Bibliographic Details
Main Authors: Jianning Zhang, Khoa Cao, Johanne V. Pastor, Liping Li, Orson W. Moe, Connie C. W. Hsia
Format: Article
Language:English
Published: Wiley 2019-11-01
Series:FASEB BioAdvances
Subjects:
Online Access:https://doi.org/10.1096/fba.2019-00016