A Cross‐Sectional Cohort Study of the Effects of FGF23 Deficiency and Hyperphosphatemia on Dental Structures in Hyperphosphatemic Familial Tumoral Calcinosis

A Cross‐Sectional Cohort Study of the Effects of FGF23 Deficiency and Hyperphosphatemia on Dental Structures in Hyperphosphatemic Familial Tumoral Calcinosis

ABSTRACT Hyperphosphatemic familial tumoral calcinosis (HFTC) is a rare autosomal recessive disorder caused by mutations in FGF23, GALNT3, KLOTHO, or FGF23 autoantibodies. Prominent features include high blood phosphate and calcific masses, usually adjacent to large joints. Dental defects have been...

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Bibliographic Details
Main Authors: Alisa E Lee, Emily Y Chu, Pamela J Gardner, Olivier Duverger, Amanda Saikali, Sean K Wang, Rachel I Gafni, Iris R Hartley, Kelly G Ten Hagen, Martha J Somerman, Michael T Collins
Format: Article
Language:English
Published: Wiley 2021-05-01
Series:JBMR Plus
Subjects:
BONE MICRO‐COMPUTED TOMOGRAPHY (μCT)
BONE QUANTITATIVE COMPUTED TOMOGRAPHY (QCT)
DENTAL BIOLOGY
DISORDERS OF CALCIUM/PHOSPHATE METABOLISM
FIBROBLAST GROWTH FACTOR 23 (FGF23)
MOLECULAR PATHWAYS—DEVELOPMENT
Online Access:https://doi.org/10.1002/jbm4.10470

Internet

https://doi.org/10.1002/jbm4.10470

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