International study to evaluate PCR methods for detection of Trypanosoma cruzi DNA in blood samples from Chagas disease patients.

BACKGROUND: A century after its discovery, Chagas disease still represents a major neglected tropical threat. Accurate diagnostics tools as well as surrogate markers of parasitological response to treatment are research priorities in the field. The purpose of this study was to evaluate the performan...

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Main Authors: Alejandro G Schijman, Margarita Bisio, Liliana Orellana, Mariela Sued, Tomás Duffy, Ana M Mejia Jaramillo, Carolina Cura, Frederic Auter, Vincent Veron, Yvonne Qvarnstrom, Stijn Deborggraeve, Gisely Hijar, Inés Zulantay, Raúl Horacio Lucero, Elsa Velazquez, Tatiana Tellez, Zunilda Sanchez Leon, Lucia Galvão, Debbie Nolder, María Monje Rumi, José E Levi, Juan D Ramirez, Pilar Zorrilla, María Flores, Maria I Jercic, Gladys Crisante, Néstor Añez, Ana M De Castro, Clara I Gonzalez, Karla Acosta Viana, Pedro Yachelini, Faustino Torrico, Carlos Robello, Patricio Diosque, Omar Triana Chavez, Christine Aznar, Graciela Russomando, Philippe Büscher, Azzedine Assal, Felipe Guhl, Sergio Sosa Estani, Alexandre DaSilva, Constança Britto, Alejandro Luquetti, Janis Ladzins
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3019106?pdf=render