Abnormal expression and methylation of PRR34‐AS1 are associated with adverse outcomes in acute myeloid leukemia

Abnormal expression and methylation of PRR34‐AS1 are associated with adverse outcomes in acute myeloid leukemia

Abstract It was previously reported that PRR34‐AS1 was overexpressed in some solid tumors. PRR34‐AS1 promoter was shown to have a differential methylation region (DMR), and was hypomethylated in acute myeloid leukemia (AML). Therefore, the present study used real‐time quantitative PCR (RQ‐PCR) to ex...

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Bibliographic Details
Main Authors: Fang‐yu Nan, Yu Gu, Zi‐jun Xu, Guo‐kang Sun, Jing‐dong Zhou, Ting‐juan Zhang, Ji‐chun Ma, Jia‐yan Leng, Jiang Lin, Jun Qian
Format: Article
Language:English
Published: Wiley 2021-08-01
Series:Cancer Medicine
Subjects:
acute myeloid leukemia
DNA methylation
expression
lncRNAs
prognosis
PRR34‐AS1
Online Access:https://doi.org/10.1002/cam4.4085

Internet

https://doi.org/10.1002/cam4.4085

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