miR-149 inhibits cell proliferation and enhances chemosensitivity by targeting CDC42 and BCL2 in neuroblastoma

Abstract Background Neuroblastoma (NB) is one of most common childhood tumors with high mortality among children worldwide. microRNAs (miRNAs) have been reported to play essential roles in the pathogenesis and therapeutics of NB. However, the role of miR-149 and its mechanism remain poorly understoo...

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Bibliographic Details
Main Authors: Fengxia Mao, Ju Zhang, Xinru Cheng, Qianya Xu
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Cancer Cell International
Subjects:
Online Access:https://doi.org/10.1186/s12935-019-1082-9