Hypoxia attenuates metabolism of platelet activating factor by fetal and newborn lamb lungs

The metabolism of platelet activating factor (PAF) by lungs of near-term fetal and 5- to 9-day-old lambs was studied during normoxia and hypoxia at 37 degrees C in 30 mM Tris buffer. PAF synthesis was studied in lung cytosol and membrane using 250 microM [3H]acetyl CoA, 40 microM lyso-PAF, and 50 mi...

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Bibliographic Details
Main Authors: A M Salva, B O Ibe, E Cliborn, G Reyes, J U Raj
Format: Article
Language:English
Published: Elsevier 1996-04-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520375763