Drug Induced Liver Injury in Geriatric Patients Detected by a Two-Hospital Prospective Pharmacovigilance Program: A Comprehensive Analysis Using the Roussel Uclaf Causality Assessment Method

Drug Induced Liver Injury in Geriatric Patients Detected by a Two-Hospital Prospective Pharmacovigilance Program: A Comprehensive Analysis Using the Roussel Uclaf Causality Assessment Method

Background/aim: A prospective evaluation of drug-induced liver injury (DILI) in two tertiary hospitals was conducted through a pharmacovigilance program from laboratory signals at hospital (PPLSH) to determine the principal characteristics of DILI in patients older than 65 years, a growing age group...

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Bibliographic Details
Main Authors: Laura Pedraza, Olga Laosa, Leocadio Rodríguez-Mañas, Diego F Gutiérrez-Romero, Jesús Frías, José Antonio Carnicero, Elena Ramírez
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Pharmacology
Subjects:
drug-induced liver injury
pharmacovigilance
elderly
adverse drug reaction
roussel uclaf causality assessment method
clinical pharmacology
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.600255/full

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https://www.frontiersin.org/articles/10.3389/fphar.2020.600255/full

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