Phenotypic and immune functional profiling of patients with suspected Mendelian Susceptibility to Mycobacterial Disease in South Africa

Phenotypic and immune functional profiling of patients with suspected Mendelian Susceptibility to Mycobacterial Disease in South Africa

Abstract Background Mendelian Susceptibility to Mycobacterial Disease (MSMD) is a primary immunodeficiency (PID) characterised by a predisposition to infection by weakly-pathogenic mycobacteria. In countries with a high prevalence of tuberculosis (TB), individuals with MSMD are also prone to infecti...

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Bibliographic Details
Main Authors: Ansia van Coller, Brigitte Glanzmann, Helena Cornelissen, Marlo Möller, Craig Kinnear, Monika Esser, Richard Glashoff
Format: Article
Language:English
Published: BMC 2021-09-01
Series:BMC Immunology
Subjects:
Mendelian Susceptibility to Mycobacterial Disease
Tuberculosis
Immune profiling
IFN-γ-IL-12 cytokine pathways
Online Access:https://doi.org/10.1186/s12865-021-00452-6

Internet

https://doi.org/10.1186/s12865-021-00452-6

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