Systematic identification of combinatorial drivers and targets in cancer cell lines.

There is an urgent need to elicit and validate highly efficacious targets for combinatorial intervention from large scale ongoing molecular characterization efforts of tumors. We established an in silico bioinformatic platform in concert with a high throughput screening platform evaluating 37 novel...

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Bibliographic Details
Main Authors: Adel Tabchy, Nevine Eltonsy, David E Housman, Gordon B Mills
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3618473?pdf=render