Inferring fitness landscapes and selection on phenotypic states from single-cell genealogical data.
Recent advances in single-cell time-lapse microscopy have revealed non-genetic heterogeneity and temporal fluctuations of cellular phenotypes. While different phenotypic traits such as abundance of growth-related proteins in single cells may have differential effects on the reproductive success of c...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-03-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC5360348?pdf=render |