Suicide Gene Therapy Mediated with Exosomes Produced by Mesenchymal Stem/Stromal Cells Stably Transduced with HSV Thymidine Kinase

Mesenchymal stem/stromal cells (MSCs) prepared from various human tissues were stably transduced with the suicide gene herpes simplex virus thymidine kinase (<i>HSVTK)</i> by means of retrovirus infection. <i>HSVTK</i>-transduced MSCs express the suicide gene and in prodrug g...

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Bibliographic Details
Main Authors: Andrea Pastorakova, Jana Jakubechova, Ursula Altanerova, Cestmir Altaner
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Cancers
Subjects:
GCV
Online Access:https://www.mdpi.com/2072-6694/12/5/1096