Real-time transcriptional profiling of cellular and viral gene expression during lytic cytomegalovirus infection.

Real-time transcriptional profiling of cellular and viral gene expression during lytic cytomegalovirus infection.

During viral infections cellular gene expression is subject to rapid alterations induced by both viral and antiviral mechanisms. In this study, we applied metabolic labeling of newly transcribed RNA with 4-thiouridine (4sU-tagging) to dissect the real-time kinetics of cellular and viral transcriptio...

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Bibliographic Details
Main Authors: Lisa Marcinowski, Michael Lidschreiber, Lukas Windhager, Martina Rieder, Jens B Bosse, Bernd Rädle, Thomas Bonfert, Ildiko Györy, Miranda de Graaf, Olivia Prazeres da Costa, Philip Rosenstiel, Caroline C Friedel, Ralf Zimmer, Zsolt Ruzsics, Lars Dölken
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-09-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3435240?pdf=render

Internet

http://europepmc.org/articles/PMC3435240?pdf=render

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