Monoclonal antibodies against accumulation-associated protein affect EPS biosynthesis and enhance bacterial accumulation of Staphylococcus epidermidis.

Because there is no effective antibiotic to eradicate Staphylococcus epidermidis biofilm infections that lead to the failure of medical device implantations, the development of anti-biofilm vaccines is necessary. Biofilm formation by S. epidermidis requires accumulation-associated protein (Aap) that...

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Bibliographic Details
Main Authors: Jian Hu, Tao Xu, Tao Zhu, Qiang Lou, Xueqin Wang, Yang Wu, Renzheng Huang, Jingran Liu, Huayong Liu, Fangyou Yu, Baixing Ding, Yalin Huang, Wenyan Tong, Di Qu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3110253?pdf=render