Concentration‐QTc Modeling of Ozanimod’s Major Active Metabolites in Adult Healthy Subjects

Ozanimod, approved by regulatory agencies in multiple countries for the treatment of adults with relapsing multiple sclerosis, is a sphingosine 1‐phosphate (S1P) receptor modulator, which binds with high affinity selectively to S1P receptor subtypes 1 and 5. The relationships between plasma concentr...

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Bibliographic Details
Main Authors: Emily Briggs, Sunny Chapel, Peijin Zhang, Maria Palmisano, Jonathan Q. Tran
Format: Article
Language:English
Published: Wiley 2021-02-01
Series:CPT: Pharmacometrics & Systems Pharmacology
Online Access:https://doi.org/10.1002/psp4.12580