Concentration‐QTc Modeling of Ozanimod’s Major Active Metabolites in Adult Healthy Subjects
Ozanimod, approved by regulatory agencies in multiple countries for the treatment of adults with relapsing multiple sclerosis, is a sphingosine 1‐phosphate (S1P) receptor modulator, which binds with high affinity selectively to S1P receptor subtypes 1 and 5. The relationships between plasma concentr...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2021-02-01
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Series: | CPT: Pharmacometrics & Systems Pharmacology |
Online Access: | https://doi.org/10.1002/psp4.12580 |