Restoration of gallstone susceptibility by leptin in C57BL/6J ob/ob mice
The absence of leptin due to the ob mutation leads to obesity and confers resistance to diet-induced cholesterol gallstone formation in otherwise susceptible C57BL/6J mice. To investigate contributions of obesity and leptin to gallstone susceptibility, C57BL/6J ob/ob mice were treated daily with i.p...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2003-06-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520311251 |