Retinoic acid inducible gene-I mediated detection of bacterial nucleic acids in human microglial cells

Retinoic acid inducible gene-I mediated detection of bacterial nucleic acids in human microglial cells

Abstract Background Bacterial meningitis and meningoencephalitis are associated with devastating neuroinflammation. We and others have demonstrated the importance of glial cells in the initiation of immune responses to pathogens invading the central nervous system (CNS). These cells use a variety of...

Full description

Bibliographic Details
Main Authors: M. Brittany Johnson, Justin R. Halman, Amanda R. Burmeister, Saralynn Currin, Emil F. Khisamutdinov, Kirill A. Afonin, Ian Marriott
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Journal of Neuroinflammation
Subjects:
RIG-I
Human
Microglia
Bacterial nucleic acids
Nucleic acid nanoparticle
Online Access:http://link.springer.com/article/10.1186/s12974-020-01817-1

Internet

http://link.springer.com/article/10.1186/s12974-020-01817-1

Similar Items