Retinoic acid inducible gene-I mediated detection of bacterial nucleic acids in human microglial cells
Abstract Background Bacterial meningitis and meningoencephalitis are associated with devastating neuroinflammation. We and others have demonstrated the importance of glial cells in the initiation of immune responses to pathogens invading the central nervous system (CNS). These cells use a variety of...
Main Authors: | M. Brittany Johnson, Justin R. Halman, Amanda R. Burmeister, Saralynn Currin, Emil F. Khisamutdinov, Kirill A. Afonin, Ian Marriott |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-05-01
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Series: | Journal of Neuroinflammation |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12974-020-01817-1 |
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