Aspirin-mediated acetylation of haemoglobin increases in presence of high glucose concentration and decreases protein glycation

Glycation represents the first stage in the development of diabetic complications. Aspirin was shown to prevent sugars reacting with proteins, but the exact mechanism of this interaction was not well defined. We performed a quantitative analysis to calculate the levels of acetylation and glycation o...

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Bibliographic Details
Main Authors: Francesco Finamore, Feliciano Priego-Capote, Severine Nolli, Pierre Fontana, Jean-Charles Sanchez
Format: Article
Language:English
Published: Elsevier 2015-09-01
Series:EuPA Open Proteomics
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2212968515000124