Lipoprotein aggregation protects human monocyte-derived macrophages from OxLDL-induced cytotoxicity

Lipoprotein aggregation protects human monocyte-derived macrophages from OxLDL-induced cytotoxicity

Oxidative modifications render low density lipoprotein cytotoxic and enhance its propensity to aggregate and fuse into particles similar to those found in atherosclerotic lesions. We showed previously that aggregation of oxidized LDL (OxLDL) promotes the transformation of human macrophages into lipi...

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Bibliographic Details
Main Authors: Reto Asmis, Jim G. Begley, Jennifer Jelk, William V. Everson
Format: Article
Language:English
Published: Elsevier 2005-06-01
Series:Journal of Lipid Research
Subjects:
cell death
atherosclerosis
oxidized low density lipoprotein
foam cells
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520330182

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http://www.sciencedirect.com/science/article/pii/S0022227520330182

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