Variants of cancer susceptibility genes in Korean BRCA1/2 mutation-negative patients with high risk for hereditary breast cancer

Variants of cancer susceptibility genes in Korean BRCA1/2 mutation-negative patients with high risk for hereditary breast cancer

Abstract Background We evaluated the incidence and spectrum of pathogenic and likely pathogenic variants of cancer susceptibility genes in BRCA1/2 mutation-negative Korean patients with a high risk for hereditary breast cancer using a comprehensive multigene panel that included 35 cancer susceptibil...

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Bibliographic Details
Main Authors: Ji Soo Park, Seung-Tae Lee, Eun Ji Nam, Jung Woo Han, Jung-Yun Lee, Jieun Kim, Tae Il Kim, Hyung Seok Park
Format: Article
Language:English
Published: BMC 2018-01-01
Series:BMC Cancer
Subjects:
Breast neoplasms
Neoplastic Syndromes, Hereditary
Beyond BRCA1/2
Multigene panel
Next generation sequencing
Online Access:http://link.springer.com/article/10.1186/s12885-017-3940-y

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http://link.springer.com/article/10.1186/s12885-017-3940-y

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