A novel role for lipid droplets in the organismal antibacterial response

A novel role for lipid droplets in the organismal antibacterial response

We previously discovered histones bound to cytosolic lipid droplets (LDs); here we show that this forms a cellular antibacterial defense system. Sequestered on droplets under normal conditions, in the presence of bacterial lipopolysaccharide (LPS) or lipoteichoic acid (LTA), histones are released fr...

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Bibliographic Details
Main Authors: Preetha Anand, Silvia Cermelli, Zhihuan Li, Adam Kassan, Marta Bosch, Robilyn Sigua, Lan Huang, Andre J Ouellette, Albert Pol, Michael A Welte, Steven P Gross
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2012-11-01
Series:eLife
Subjects:
innate immunity
histone
lipid droplet
anti-bacterial
Online Access:https://elifesciences.org/articles/00003

Internet

https://elifesciences.org/articles/00003

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