Autoantibodies in Systemic Lupus Erythematosus Target Mitochondrial RNA

Autoantibodies in Systemic Lupus Erythematosus Target Mitochondrial RNA

The mitochondrion supplies energy to the cell and regulates apoptosis. Unlike other mammalian organelles, mitochondria are formed by binary fission and cannot be directly produced by the cell. They contain numerous copies of a compact circular genome that encodes RNA molecules and proteins involved...

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Bibliographic Details
Main Authors: Yann Becker, Geneviève Marcoux, Isabelle Allaeys, Anne-Sophie Julien, Renée-Claude Loignon, Hadrien Benk-Fortin, Emmanuelle Rollet-Labelle, Joyce Rauch, Paul R. Fortin, Eric Boilard
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Immunology
Subjects:
autoantibodies-blood
mitochondria-RNA
antimitochondrial antibody (AMA)
autoimmue disease
systemic lupus erythematosus (SLE)
autoantigens
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01026/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01026/full

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