Hemolytic reaction in the washed salvaged blood of a patient with paroxysmal nocturnal hemoglobinuria

Hemolytic reaction in the washed salvaged blood of a patient with paroxysmal nocturnal hemoglobinuria

Abstract Background In patients with paroxysmal nocturnal hemoglobinuria (PNH), the membrane-attack complex (MAC) formed on red blood cells (RBCs) causes hemolysis due to the patient’s own activated complement system by an infection, inflammation, or surgical stress. The efficacy of transfusion ther...

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Bibliographic Details
Main Authors: Yuko Kawamoto, Tasuku Nishihara, Aisa Watanabe, Kazuo Nakanishi, Taisuke Hamada, Amane Konishi, Naoki Abe, Sakiko Kitamura, Keizo Ikemune, Yuichiro Toda, Toshihiro Yorozuya
Format: Article
Language:English
Published: BMC 2019-05-01
Series:BMC Anesthesiology
Subjects:
Paroxysmal nocturnal hemoglobinuria
Blood salvage device
Autologous blood transfusion
Complement
Hemolysis
Hyperkalemia
Online Access:http://link.springer.com/article/10.1186/s12871-019-0752-4

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http://link.springer.com/article/10.1186/s12871-019-0752-4

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