Peptides derived from the integrin β cytoplasmic tails inhibit angiogenesis

Peptides derived from the integrin β cytoplasmic tails inhibit angiogenesis

Abstract Background Integrins are essential regulators of angiogenesis. However, the antiangiogenic potential of peptides derived from the integrin cytoplasmic tails (CT) remains mostly undetermined. Methods Here we designed a panel of membrane-penetrating peptides (termed as mβCTPs), each comprisin...

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Bibliographic Details
Main Authors: Zhongyuan Cao, Xinfeng Suo, Yudan Chu, Zhou Xu, Yun Bao, Chunxiao Miao, Wenfeng Deng, Kaijun Mao, Juan Gao, Zhen Xu, Yan-Qing Ma
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Cell Communication and Signaling
Subjects:
Angiogenesis
Endothelial cells
Integrins
Cytoplasmic tails
β3-endonexin
Online Access:http://link.springer.com/article/10.1186/s12964-018-0248-8

Internet

http://link.springer.com/article/10.1186/s12964-018-0248-8

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