Ubiquitination and SUMOylation in Telomere Maintenance and Dysfunction

Telomeres are essential nucleoprotein structures at linear chromosomes that maintain genome integrity by protecting chromosome ends from being recognized and processed as damaged DNA. In addition, they limit the cell’s proliferative capacity, as progressive loss of telomeric DNA during successive ro...

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Bibliographic Details
Main Authors: Zeliha Yalçin, Carolin Selenz, Jacqueline J. L. Jacobs
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fgene.2017.00067/full