Human Platelet Mitochondrial Function Reflects Systemic Mitochondrial Alterations: A Protocol for Application in Field Studies

Human blood cells may offer a minimally invasive strategy to study systemic alterations of mitochondrial function. Here we tested the reliability of a protocol designed to study mitochondrial respiratory control in human platelets (PLTs) in field studies, using high-resolution respirometry (HRR). Se...

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Bibliographic Details
Main Authors: Florian Hoppel, Luiz Felipe Garcia-Souza, Wilhelm Kantner-Rumplmair, Martin Burtscher, Erich Gnaiger, Dominik Pesta, Elisa Calabria
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/10/8/2088