Founder mutations characterise the mutation panorama in 200 Swedish index cases referred for Long QT syndrome genetic testing

Founder mutations characterise the mutation panorama in 200 Swedish index cases referred for Long QT syndrome genetic testing

<p>Abstract</p> <p>Background</p> <p>Long QT syndrome (LQTS) is an inherited arrhythmic disorder characterised by prolongation of the QT interval on ECG, presence of syncope and sudden death. The symptoms in LQTS patients are highly variable, and genotype influences the...

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Bibliographic Details
Main Authors: Stattin Eva-Lena, Boström Ida, Winbo Annika, Cederquist Kristina, Jonasson Jenni, Jonsson Björn-Anders, Diamant Ulla-Britt, Jensen Steen M, Rydberg Annika, Norberg Anna
Format: Article
Language:English
Published: BMC 2012-10-01
Series:BMC Cardiovascular Disorders
Subjects:
Arrhythmia
Long QT syndrome
Ion-channel
Founder mutation
Variant of unknown significance
Online Access:http://www.biomedcentral.com/1471-2261/12/95

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http://www.biomedcentral.com/1471-2261/12/95

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