TUBB3 Reverses Resistance to Docetaxel and Cabazitaxel in Prostate Cancer

TUBB3 Reverses Resistance to Docetaxel and Cabazitaxel in Prostate Cancer

Recent studies have reported that TUBB3 overexpression is involved in docetaxel (DTX) resistance in prostate cancer (PCa). The aim of this study was to clarify the role of TUBB3 in DTX and cabazitaxel (CBZ) resistance, and cross-resistance between DTX and CBZ in PCa. We analyzed the effect of TUBB3...

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Bibliographic Details
Main Authors: Yohei Sekino, Xiangrui Han, Takafumi Kawaguchi, Takashi Babasaki, Keisuke Goto, Shogo Inoue, Tetsutaro Hayashi, Jun Teishima, Masaki Shiota, Wataru Yasui, Akio Matsubara
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:International Journal of Molecular Sciences
Subjects:
prostate cancer
TUBB3
PTEN
docetaxel
cabazitaxel
cross-resistance
LY294002
Online Access:https://www.mdpi.com/1422-0067/20/16/3936

Internet

https://www.mdpi.com/1422-0067/20/16/3936

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