Multi-Stress Induction of the <i>Mycobacterium tuberculosis</i> MbcTA Bactericidal Toxin-Antitoxin System
MbcTA is a type II toxin/antitoxin (TA) system of <i>Mycobacterium tuberculosis</i>. The MbcT toxin triggers mycobacterial cell death in vitro and in vivo through the phosphorolysis of the essential metabolite NAD<sup>+</sup> and its bactericidal activity is neutralized by ph...
Main Authors: | Kanchiyaphat Ariyachaokun, Anna D. Grabowska, Claude Gutierrez, Olivier Neyrolles |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-05-01
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Series: | Toxins |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6651/12/5/329 |
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