Treatment with Tumor Necrosis Factor-α Inhibitors, History of Allergy, and Hypercalcemia Are Risk Factors of Immune Reconstitution Inflammatory Syndrome in HIV-Negative Pulmonary Tuberculosis Patients

Treatment with Tumor Necrosis Factor-α Inhibitors, History of Allergy, and Hypercalcemia Are Risk Factors of Immune Reconstitution Inflammatory Syndrome in HIV-Negative Pulmonary Tuberculosis Patients

Immune reconstitution inflammatory syndrome (IRIS) is an immune reaction that occurs along with the recovery of the patient’s immunity. Tuberculosis-related IRIS (TB-IRIS) upon tumor necrosis factor (TNF)-α inhibitor treatment has been reported in non-human immunodeficiency virus...

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Bibliographic Details
Main Authors: Yoshimasa Hachisu, Yasuhiko Koga, Shu Kasama, Kyoichi Kaira, Masakiyo Yatomi, Haruka Aoki-Saito, Hiroaki Tsurumaki, Yosuke Kamide, Noriaki Sunaga, Toshitaka Maeno, Tamotsu Ishizuka, Takeshi Hisada
Format: Article
Language:English
Published: MDPI AG 2019-12-01
Series:Journal of Clinical Medicine
Subjects:
tnf-α inhibitor
tnfi
tuberculosis
paradoxical response
immune reconstitution inflammatory syndrome
iris
history of allergy
hypercalcemia
th1
th2
Online Access:https://www.mdpi.com/2077-0383/9/1/96

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https://www.mdpi.com/2077-0383/9/1/96

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