Time-Dependent Phenotypic and Contractile Changes of Pulmonary Artery in Chronic Hypoxia–Induced Pulmonary Hypertension

Abstract.: Phenotypic and contractile changes in pulmonary arterial smooth muscle cells (PASMCs) were examined in rats with pulmonary hypertension induced by hypoxia. Exposure to hypoxia induced pulmonary hypertension within 1 – 4 weeks. Staining with BrdU revealed that proliferative activities of P...

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Bibliographic Details
Main Authors: Daigo Aoshima, Takahisa Murata, Masatoshi Hori, Hiroshi Ozaki
Format: Article
Language:English
Published: Elsevier 2009-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319311934