Excitatory synaptic transmission in hippocampal area CA1 is enhanced then reduced as chronic epilepsy progresses
This study examines changes in synaptic transmission with progression of the chronic epileptic state. Male Sprague-Dawley rats (P40–45) were injected with either saline or pilocarpine. In rats injected with pilocarpine, status epilepticus ensued. Hippocampal slices were cut 20–60 days or 80–110 days...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-07-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996121000929 |