Beyond cancer genes: colorectal cancer as robust intrinsic states formed by molecular interactions

Beyond cancer genes: colorectal cancer as robust intrinsic states formed by molecular interactions

Colorectal cancer (CRC) has complex pathological features that defy the linear-additive reasoning prevailing in current biomedicine studies. In pursuing a mechanistic understanding behind such complexity, we constructed a core molecular–cellular interaction network underlying CRC and investigated it...

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Bibliographic Details
Main Authors: Ruoshi Yuan, Suzhan Zhang, Jiekai Yu, Yanqin Huang, Demin Lu, Runtan Cheng, Sui Huang, Ping Ao, Shu Zheng, Leroy Hood, Xiaomei Zhu
Format: Article
Language:English
Published: The Royal Society 2017-01-01
Series:Open Biology
Subjects:
colorectal cancer
systems biology
robust dynamical states
endogenous molecular–cellular network
stochastic nonlinear dynamics
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.170169

Internet

https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.170169

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