Immunogenicity test of tetanus component in adsorbed vaccines by toxin binding inhibition test

Immunogenicity test of tetanus component in adsorbed vaccines by toxin binding inhibition test

Samples from 20 lots of diphtheria-tetanus (adult use dT) vaccine and from 20 lots of diphtheria-tetanus-pertussis (DTP) vaccine were used to standardize and validate the in vitro toxin binding inhibition (ToBI) test for the immunogenicity test of the tetanus component. The levels of tetanus antitox...

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Bibliographic Details
Main Authors: Denise Cristina Souza Matos, Rugimar Marcovistz, Pedro Hernan Cabello, Ricardo Amaral Georgini, Dirce Sakauchi, Luciana Leite da Silva
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2002-09-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
diphtheria-tetanus vaccine
diphtheria-tetanus-pertussis vaccine
toxin binding inhibition test
tetanus
quality control
seroneutralization
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762002000600030

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762002000600030

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