The interaction of neuroimmunology, neuromodulator, and neurotransmitter with nociceptor and MAPK signaling
Physiological pain is a protection mechanism against tissue damage or potential tissue damage. Inflammation pain is followed by tissue damage due to temperature, mechanical and chemical stimuli which increase crosstalk between neuron nociceptor, immune system, neuromodulator and neurotransmitter, an...
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Wolters Kluwer Medknow Publications
2019-01-01
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Series: | Bali Journal of Anesthesiology |
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doaj-26fbf2ee74384903bd468ad614f4a75b2021-07-27T04:13:32ZengWolters Kluwer Medknow PublicationsBali Journal of Anesthesiology2549-22762019-01-0131444910.15562/bjoa.v3i1.134The interaction of neuroimmunology, neuromodulator, and neurotransmitter with nociceptor and MAPK signalingDewa Ayu Mas Shintya DewiMade WiryanaPhysiological pain is a protection mechanism against tissue damage or potential tissue damage. Inflammation pain is followed by tissue damage due to temperature, mechanical and chemical stimuli which increase crosstalk between neuron nociceptor, immune system, neuromodulator and neurotransmitter, and MAPK (Mitogen Activating Protein Kinase) signal. Initially, immune cell is produced at the primary afferent nerve endings and spinal cord, modulate thermal sensitivity and mechanic through MAPK signaling, then neuromodulator and neurotransmitter at the afferent nerve endings will regulate the innate immune response, adaptive and vascularhttp://www.bjoaonline.com/article.asp?issn=2549-2276;year=2019;volume=3;issue=1;spage=44;epage=49;aulast=Shintya;type=0neuroimmunologyneuromodulatorneurotransmittersensory neuroninflammation pain |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Dewa Ayu Mas Shintya Dewi Made Wiryana |
spellingShingle |
Dewa Ayu Mas Shintya Dewi Made Wiryana The interaction of neuroimmunology, neuromodulator, and neurotransmitter with nociceptor and MAPK signaling Bali Journal of Anesthesiology neuroimmunology neuromodulator neurotransmitter sensory neuron inflammation pain |
author_facet |
Dewa Ayu Mas Shintya Dewi Made Wiryana |
author_sort |
Dewa Ayu Mas Shintya Dewi |
title |
The interaction of neuroimmunology, neuromodulator, and neurotransmitter with nociceptor and MAPK signaling |
title_short |
The interaction of neuroimmunology, neuromodulator, and neurotransmitter with nociceptor and MAPK signaling |
title_full |
The interaction of neuroimmunology, neuromodulator, and neurotransmitter with nociceptor and MAPK signaling |
title_fullStr |
The interaction of neuroimmunology, neuromodulator, and neurotransmitter with nociceptor and MAPK signaling |
title_full_unstemmed |
The interaction of neuroimmunology, neuromodulator, and neurotransmitter with nociceptor and MAPK signaling |
title_sort |
interaction of neuroimmunology, neuromodulator, and neurotransmitter with nociceptor and mapk signaling |
publisher |
Wolters Kluwer Medknow Publications |
series |
Bali Journal of Anesthesiology |
issn |
2549-2276 |
publishDate |
2019-01-01 |
description |
Physiological pain is a protection mechanism against tissue damage or potential tissue damage. Inflammation pain is followed by tissue damage due to temperature, mechanical and chemical stimuli which increase crosstalk between neuron nociceptor, immune system, neuromodulator and neurotransmitter, and MAPK (Mitogen Activating Protein Kinase) signal. Initially, immune cell is produced at the primary afferent nerve endings and spinal cord, modulate thermal sensitivity and mechanic through MAPK signaling, then neuromodulator and neurotransmitter at the afferent nerve endings will regulate the innate immune response, adaptive and vascular |
topic |
neuroimmunology neuromodulator neurotransmitter sensory neuron inflammation pain |
url |
http://www.bjoaonline.com/article.asp?issn=2549-2276;year=2019;volume=3;issue=1;spage=44;epage=49;aulast=Shintya;type=0 |
work_keys_str_mv |
AT dewaayumasshintyadewi theinteractionofneuroimmunologyneuromodulatorandneurotransmitterwithnociceptorandmapksignaling AT madewiryana theinteractionofneuroimmunologyneuromodulatorandneurotransmitterwithnociceptorandmapksignaling AT dewaayumasshintyadewi interactionofneuroimmunologyneuromodulatorandneurotransmitterwithnociceptorandmapksignaling AT madewiryana interactionofneuroimmunologyneuromodulatorandneurotransmitterwithnociceptorandmapksignaling |
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