Activation of Anthracene Endoperoxides in Leishmania and Impairment of Mitochondrial Functions

Activation of Anthracene Endoperoxides in Leishmania and Impairment of Mitochondrial Functions

Leishmaniasis is a vector-borne disease caused by protozoal Leishmania. Because of resistance development against current drugs, new antileishmanial compounds are urgently needed. Endoperoxides (EPs) are successfully used in malaria therapy, and experimental evidence of their potential against leish...

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Bibliographic Details
Main Authors: Gerald Geroldinger, Matthias Tonner, Werner Fudickar, Sritama De Sarkar, Aishwarya Dighal, Lianet Monzote, Katrin Staniek, Torsten Linker, Mitali Chatterjee, Lars Gille
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Molecules
Subjects:
Leishmania
endoperoxides
EPR spectroscopy
mitochondria
radicals
Online Access:http://www.mdpi.com/1420-3049/23/7/1680

Internet

http://www.mdpi.com/1420-3049/23/7/1680

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