Fast batch searching for protein homology based on compression and clustering

Abstract Background In bioinformatics community, many tasks associate with matching a set of protein query sequences in large sequence datasets. To conduct multiple queries in the database, a common used method is to run BLAST on each original querey or on the concatenated queries. It is inefficient...

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Bibliographic Details
Main Authors: Hongwei Ge, Liang Sun, Jinghong Yu
Format: Article
Language:English
Published: BMC 2017-11-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-017-1938-8