Quantitative analysis of mechanical force required for cell extrusion in zebrafish embryonic epithelia

When cells in epithelial sheets are damaged by intrinsic or extrinsic causes, they are eliminated by extrusion from the sheet. Cell extrusion, which is required for maintenance of tissue integrity, is the consequence of contraction of actomyosin rings, as demonstrated by both molecular/cellular biol...

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Bibliographic Details
Main Authors: Sohei Yamada, Takanori Iino, Yasumasa Bessho, Yoichiroh Hosokawa, Takaaki Matsui
Format: Article
Language:English
Published: The Company of Biologists 2017-10-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/6/10/1575