Infection of sympathetic and sensory neurones with herpes simplex virus does not elicit a shut-off of cellular protein synthesis: implications for viral latency and herpes vectors
Infection of non-neuronal cell types with herpes simplex virus type 1 (HSV-1) results in the degradation of host mRNA (Kwong & Frenkel 1987) and a shutoff in host protein synthesis (Roizmanet al.1965). This effect is mediated by a virion associated protein that is encoded by the viralvhsgene...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
1994-11-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996184700118 |