Repurposing antimalarial aminoquinolines and related compounds for treatment of retinal neovascularization.

Neovascularization is the pathological driver of blinding eye diseases such as retinopathy of prematurity, proliferative diabetic retinopathy, and wet age-related macular degeneration. The loss of vision resulting from these diseases significantly impacts the productivity and quality of life of pati...

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Bibliographic Details
Main Authors: Danielle McAnally, Khandaker Siddiquee, Ahmed Gomaa, Andras Szabo, Stefan Vasile, Patrick R Maloney, Daniela B Divlianska, Satyamaheshwar Peddibhotla, Camilo J Morfa, Paul Hershberger, Rebecca Falter, Robert Williamson, David B Terry, Rafal Farjo, Anthony B Pinkerton, Xiaping Qi, Judith Quigley, Michael E Boulton, Maria B Grant, Layton H Smith
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6135396?pdf=render