Structural Analysis of the SANT/Myb Domain of FLASH and YARP Proteins and Their Complex with the C-Terminal Fragment of NPAT by NMR Spectroscopy and Computer Simulations

Structural Analysis of the SANT/Myb Domain of FLASH and YARP Proteins and Their Complex with the C-Terminal Fragment of NPAT by NMR Spectroscopy and Computer Simulations

FLICE-associated huge protein (FLASH), Yin Yang 1-Associated Protein-Related Protein (YARP) and Nuclear Protein, Ataxia-Telangiectasia Locus (NPAT) localize to discrete nuclear structures called histone locus bodies (HLBs) where they control various steps in histone gene expression. Near the C-termi...

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Bibliographic Details
Main Authors: Katarzyna Bucholc, Aleksandra Skrajna, Kinga Adamska, Xiao-Cui Yang, Krzysztof Krajewski, Jarosław Poznański, Michał Dadlez, Zbigniew Domiński, Igor Zhukov
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:International Journal of Molecular Sciences
Subjects:
Histone locus body
SANT domain
Myb DNA binding domain
NMR spectroscopy
Online Access:https://www.mdpi.com/1422-0067/21/15/5268

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https://www.mdpi.com/1422-0067/21/15/5268

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