Ancestral Variations of the PCDHG Gene Cluster Predispose to Dyslexia in a Multiplex Family

Ancestral Variations of the PCDHG Gene Cluster Predispose to Dyslexia in a Multiplex Family

Dyslexia is a heritable neurodevelopmental disorder characterized by difficulties in reading and writing. In this study, we describe the identification of a set of 17 polymorphisms located across 1.9 Mb region on chromosome 5q31.3, encompassing genes of the PCDHG cluster, TAF7, PCDH1 and ARHGAP26, d...

Full description

Bibliographic Details
Main Authors: Teesta Naskar, Mohammed Faruq, Priyajit Banerjee, Massarat Khan, Rashi Midha, Renu Kumari, Subhashree Devasenapathy, Bharat Prajapati, Sanghamitra Sengupta, Deepti Jain, Mitali Mukerji, Nandini Chatterjee Singh, Subrata Sinha
Format: Article
Language:English
Published: Elsevier 2018-02-01
Series:EBioMedicine
Subjects:
Dyslexia
Protocadherin gamma
Ancestral variations
Neanderthal genome
Dominant inheritance
Trans-homophilic interaction
Neuronal connection
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396417305121

Internet

http://www.sciencedirect.com/science/article/pii/S2352396417305121

Similar Items