<i>HTR1A, HTR1B, HTR2A, HTR2C</i> and <i>HTR6</i> Gene Polymorphisms and Extrapyramidal Side Effects in Haloperidol-Treated Patients with Schizophrenia

<i>HTR1A, HTR1B, HTR2A, HTR2C</i> and <i>HTR6</i> Gene Polymorphisms and Extrapyramidal Side Effects in Haloperidol-Treated Patients with Schizophrenia

Schizophrenia is a serious, chronic psychiatric disorder requiring lifelong treatment. Extrapyramidal side effects (EPS) are common adverse reactions to antipsychotic medications. In addition to the dopaminergic system, serotonergic mechanisms, including serotonin (5-HT) receptors, might be involved...

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Bibliographic Details
Main Authors: Mirko Grubor, Maja Zivkovic, Marina Sagud, Matea Nikolac Perkovic, Alma Mihaljevic-Peles, Nela Pivac, Dorotea Muck-Seler, Dubravka Svob Strac
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:International Journal of Molecular Sciences
Subjects:
schizophrenia
haloperidol
acute extrapyramidal side effects
serotonin receptors
gene polymorphisms
<i>HTR1B</i> gene polymorphism
Online Access:https://www.mdpi.com/1422-0067/21/7/2345

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https://www.mdpi.com/1422-0067/21/7/2345

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